IRIS: time-structured manifold projections

High-dimensional biomedical data, such as cell-by-gene matrices, are increasingly generated temporally. However, Manifold Learning algorithms, like t-SNE and UMAP, cannot incorporate time-ordering in their layouts, obfuscating the dynamics of cell types or other classes. As a solution, we present IRIS, a new Manifold Learning algorithm that structures layouts both chronologically and by manifold topology. IRIS can visualize a wide range of dynamic biomedical data, including scRNA-seq, comparative metagenomics, and literature.

Finding the Correct Visual Evidence Without Forgetting: Mitigating Hallucination in LVLMs via Inter-Layer Visual Attention Discrepancy

Large Vision-Language Models (LVLMs) have shown remarkable performance on a wide range of vision-language tasks. Despite this progress, they are still prone to hallucination, generating responses that are inconsistent with visual content. In this work, we find that LVLMs tend to hallucinate when they pay insufficient attention to the correct visual evidence and gradually forget it during the generation process. We empirically find that although LVLMs overall attend insufficiently to visual evidence, they exhibit sensitivity to the correct visual evidence in specific layers, with notable inter-layer discrepancy. Motivated by this observation, we propose a novel hallucination mitigation method that enhances visual evidence based on Inter-Layer Visual Attention Discrepancy (ILVAD). Specifically, we obtain the attention weights from early generated tokens to visual tokens across layers and identify the tokens that are repeatedly activated as visual evidence, forming a saliency map. We then enhance attention to visual evidence during generation through the saliency map to reduce visual forgetting. In addition, we leverage the saliency map to obtain attention scores of generated text to visual evidence, in order to select and emphasize text tokens that are strongly grounded in visual evidence. Our method is training-free and plug-and-play. Multiple benchmark evaluations conducted on five recently released models show that our method can consistently mitigate hallucinations in different LVLMs over various architectures. Code is available at https://github.com/ytx-ML/ILVAD.

Towards Physically Consistent 4D Scene Reconstruction for Closed-loop Autonomous Driving Simulation

High-fidelity street scene reconstruction is pivotal for end-to-end autonomous driving simulation, where novel-view synthesis (NVS) and time-varying information modeling are two fundamental capabilities to facilitate closed-loop training. However, existing 3DGS methods and their 4D extensions fail to simultaneously achieve both. To bridge this gap, we establish an information-geometric diagnostic framework, revealing that this limitation stems from a credit assignment dilemma between spatial and temporal parameters. Specifically, the deterministic coupling between viewpoint and time in single-source observation creates a low-rank structure that induces massive null-space ambiguity between static view-dependent and dynamic time-varying components. Temporal information overshadows spatial cues, causing the estimation variance of spatial parameters to diverge. To address this issue, we propose Orthogonal Projected Gradient (OPG), a hierarchical training method designed to restore spatial identifiability. OPG prioritizes the integrity of spatial representations by securing them in an initial stage, then restricts temporal updates to the spatial null space, enabling proactive credit assignment. While OPG isolates temporal updates algebraically, Temporal Regularization Strategy is proposed to further refine the temporal solution space by imposing a smoothness constraint based on the physical prior of consistent appearance evolution, ensuring that the reconstructed scene remains physically consistent in closed-loop simulation. Extensive experiments demonstrate that our method not only maintains stable NVS capabilities but also demonstrates superior performance in traditional observation-reproducing metrics, which indirectly reflect the capability of modeling temporal dynamics.

CA-GCL: Cross-Anatomy Global-Local Contrastive Learning for Robust 3D Medical Image Understanding

Fine-grained Vision-Language Pre-training (FVLP) demonstrates significant potential in 3D medical image understanding by aligning anatomy-level visual representations with corresponding textual descriptions. However, existing FVLP paradigms often suffer from severe representation collapse in the textual embedding space, where text embeddings of distinct anatomical structures become highly clustered and indistinguishable. This distributional degeneracy renders the model hypersensitive to prompt variations, hindering reliable clinical deployment. To address these challenges, we propose a novel Cross-Anatomy Global-Local Contrastive Learning framework (CA-GCL). CA-GCL introduces a global contrastive objective that enforces separation between anatomical categories in the latent space, effectively counteracting the aggregation tendency induced by local alignment. Furthermore, we incorporate a clinical-aware text augmentation strategy based on permutation invariance and partial completeness to enhance robustness against descriptive incompleteness. Extensive evaluations on the CT-RATE and Rad-ChestCT datasets demonstrate that CA-GCL consistently outperforms existing VLP paradigms in zero-shot abnormality detection, achieving superior performance while exhibiting strong cross-dataset generalization. Crucially, CA-GCL reduces performance variance across diverse prompt templates, transforming the collapsed textual similarity distribution into a bell-shaped distribution. These results validate CA-GCL as an effective framework for robust 3D medical image understanding.

Unveiling Deepfakes: A Frequency-Aware Triple Branch Network for Deepfake Detection

Advanced deepfake technologies are blurring the lines between real and fake, presenting both revolutionary opportunities and alarming threats. While it unlocks novel applications in fields like entertainment and education, its malicious use has sparked urgent ethical and societal concerns ranging from identity theft to the dissemination of misinformation. To tackle these challenges, feature analysis using frequency features has emergedas a promising direction for deepfake detection. However, oneaspect that has been overlooked so far is that existing methodstend to concentrate on one or a few specific frequency domains,which risks overfitting to particular artifacts and significantlyundermines their robustness when facing diverse forgery patterns. Another underexplored aspect we observe is that different features often attend to the same forged region, resulting in redundant feature representations and limiting the diversity of the extracted clues. This may undermine the ability of a model to capture complementary information across different facets, thereby compromising its generalization capability to diverse manipulations. In this paper, we seek to tackle these challenges from two aspects: (1) we propose a triple-branch network that jointly captures spatial and frequency features by learning from both original image and image reconstructed by different frequency channels, and (2) we mathematically derive feature decoupling and fusion losses grounded in the mutual information theory, which enhances the model to focus on task-relevant features across the original image and the image reconstructed by different frequency channels. Extensive experiments on six large-scale benchmark datasets demonstrate that our method consistently achieves state-of-the-art performance. Our code is released at https://github.com/injooker/Unveiling Deepfake.

See Fair, Speak Truth: Equitable Attention Improves Grounding and Reduces Hallucination in Vision-Language Alignment

Multimodal large language models (MLLMs) frequently hallucinate objects that are absent from the visual input, often because attention during decoding is disproportionately drawn to visually dominant or frequently occurring content. We observe that this inequity in attention allocation is a root cause of object hallucination: when rare, small, or contextually peripheral objects receive insufficient attention, the model fails to ground its generation in the full visual scene. We argue that every object in an image, regardless of its size, frequency or visual salience, deserves equal representational opportunity during decoding. To this end, we propose DOP-OBC, a training-free and architecture-agnostic decoding strategy built on the principle of equitable attention. Two complementary object-aware signals work in tandem: a Dominant Object Penalty (DOP) that softly suppresses attention over-concentration on visually dominant regions, and an Outlier Boost Coefficient (OBC) that amplifies attention toward rare yet confidently detected objects. These signals are injected as per-row logit modulations within the causal attention mask, requiring no weight updates and preserving autoregressive decoding properties. Extensive experiments across image and video MLLMs demonstrate consistent reductions in object hallucination on CHAIR and POPE benchmarks, alongside improvements in GPT-4o assessed captioning quality across correctness, consistency, detail, context and temporal dimensions. DOP-OBC establishes that fairness in attention allocation is not merely a design principle but a practical and effective path toward more faithful multimodal generation.

Beyond the Global Scores: Fine-Grained Token Grounding as a Robust Detector of LVLM Hallucinations

Large vision-language models (LVLMs) achieve strong performance on visual reasoning tasks but remain highly susceptible to hallucination. Existing detection methods predominantly rely on coarse, whole-image measures of how an object token relates to the input image. This global strategy is limited: hallucinated tokens may exhibit weak but widely scattered correlations across many local regions, which aggregate into deceptively high overall relevance, thus evading the current global hallucination detectors. We begin with a simple yet critical observation: a faithful object token must be strongly grounded in a specific image region. Building on this insight, we introduce a patch-level hallucination detection framework that examines fine-grained token-level interactions across model layers. Our analysis uncovers two characteristic signatures of hallucinated tokens: (i) they yield diffuse, non-localized attention patterns, in contrast to the compact, well-focused attention seen in faithful tokens; and (ii) they fail to exhibit meaningful semantic alignment with any visual region. Guided by these findings, we develop a lightweight and interpretable detection method that leverages patch-level statistical features, combined with hidden-layer representations. Our approach achieves up to 90% accuracy in token-level hallucination detection, demonstrating the superiority of fine-grained structural analysis for detecting hallucinations.

MedObvious: Exposing the Medical Moravec's Paradox in VLMs via Clinical Triage

Vision Language Models (VLMs) are increasingly used for tasks like medical report generation and visual question answering. However, fluent diagnostic text does not guarantee safe visual understanding. In clinical practice, interpretation begins with pre-diagnostic sanity checks: verifying that the input is valid to read (correct modality and anatomy, plausible viewpoint and orientation, and no obvious integrity violations). Existing benchmarks largely assume this step is solved, and therefore miss a critical failure mode: a model can produce plausible narratives even when the input is inconsistent or invalid. We introduce MedObvious, a 1,880-task benchmark that isolates input validation as a set-level consistency capability over small multi-panel image sets: the model must identify whether any panel violates expected coherence. MedObvious spans five progressive tiers, from basic orientation/modality mismatches to clinically motivated anatomy/viewpoint verification and triage-style cues, and includes five evaluation formats to test robustness across interfaces. Evaluating 17 different VLMs, we find that sanity checking remains unreliable: several models hallucinate anomalies on normal (negative-control) inputs, performance degrades when scaling to larger image sets, and measured accuracy varies substantially between multiple-choice and open-ended settings. These results show that pre-diagnostic verification remains unsolved for medical VLMs and should be treated as a distinct, safety-critical capability before deployment.

AURORA: Adaptive Unified Representation for Robust Ultrasound Analysis

Ultrasound images vary widely across scanners, operators, and anatomical targets, which often causes models trained in one setting to generalize poorly to new hospitals and clinical conditions. The Foundation Model Challenge for Ultrasound Image Analysis (FMC-UIA) reflects this difficulty by requiring a single model to handle multiple tasks, including segmentation, detection, classification, and landmark regression across diverse organs and datasets. We propose a unified multi-task framework based on a transformer visual encoder from the Qwen3-VL family. Intermediate token features are projected into spatial feature maps and fused using a lightweight multi-scale feature pyramid, enabling both pixel-level predictions and global reasoning within a shared representation. Each task is handled by a small task-specific prediction head, while training uses task-aware sampling and selective loss balancing to manage heterogeneous supervision and reduce task imbalance. Our method is designed to be simple to optimize and adaptable across a wide range of ultrasound analysis tasks. The performance improved from 67% to 85% on the validation set and achieved an average score of 81.84% on the official test set across all tasks. The code is publicly available at: https://github.com/saitejalekkala33/FMCUIA-ISBI.git

ClinCoT: Clinical-Aware Visual Chain-of-Thought for Medical Vision Language Models

Medical Vision-Language Models have shown promising potential in clinical decision support, yet they remain prone to factual hallucinations due to insufficient grounding in localized pathological evidence. Existing medical alignment methods primarily operate at the response level through preference optimization, improving output correctness but leaving intermediate reasoning weakly connected to visual regions. Although chain-of-thought (CoT) enhances multimodal reasoning, it remains largely text-centric, limiting effective integration of clinical visual cues. To address this gap, we propose ClinCoT, a clinical-aware visual chain-of-thought framework that transforms preference optimization from response-level correction to visual-driven reasoning. We introduce an automatic data generation pipeline that constructs clinically grounded preference pairs through reasoning with hypotheses-driven region proposals. Multiple Med-LLMs evaluators rank and assign scores to each response, and these rankings serve as supervision to train the target model. We further introduce a scoring-based margin-aware optimization strategy that incorporates both preference ranking and score difference to refine region-level reasoning trajectories. To maintain alignment as the model's policy evolves during training, we adopt an iterative learning scheme that dynamically regenerates preference data. Extensive experiments on three medical VQA and report generation benchmarks demonstrate that ClinCoT consistently improves factual grounding and achieves superior performance compared with existing preference-based alignment methods.